Dados genômicos, metabolômicos e biossintéticos de actinobactérias com atividade antifúngica

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Giordano, Ana Luisa Perini Leme; Schreiber, Angelica Zaninelli; Fantinatti-Garboggini, Fabiana, 2026, "Dados genômicos, metabolômicos e biossintéticos de actinobactérias com atividade antifúngica", https://doi.org/10.25824/redu/E06QWN, Repositório de Dados de Pesquisa da Unicamp, V1
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Description
Este conjunto de dados reúne sequências do gene 16S rRNA, genomas bacterianos montados e espectros de MALDI-TOF obtidos de actinobactérias com atividade antifúngica isoladas da biodiversidade brasileira. Os dados incluem: • sequências do gene 16S rRNA utilizadas para autenticação taxonômica das linhagens bacterianas; • genomas bacterianos montados obtidos por sequenciamento de nova geração; • arquivos de espectrometria de massas MALDI-TOF (formato mzXML) utilizados para autenticação taxonômica e avaliação de pureza dos isolados. Os genomas montados encontram-se também depositados no NCBI sob o BioProject PRJNA1418131. Os dados metabolômicos associados ao projeto foram processados e disponibilizados na plataforma GNPS (Global Natural Products Social Molecular Networking), utilizada para análises de molecular networking e comparação com bibliotecas espectrais públicas. Os respectivos links de acesso e identificadores das análises encontram-se descritos nas publicações científicas associadas ao projeto. Os arquivos estão organizados por categoria de dado e acompanhados de documentação descritiva (README e dicionário de dados). Os dados foram gerados durante o desenvolvimento da tese de doutorado da autora na Universidade Estadual de Campinas (UNICAMP), financiada pela Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, processo 2022/16198-3). (2026-04-27)
Subject Medicine, Health and Life Sciences
Keyword Biobancos, Produtos naturais, Descoberta de drogas, Agentes antifúngicos
Related Publication Giordano, Ana Luisa Perini Leme, Marili Villa Nova Rodrigues, Karen Gabriela Araujo dos Santos, Barbara Cipulo Legabão, Lais Pontes, Derlene Attili de Angelis, Fabiana Fantinatti Garboggini, and Angelica Zaninelli Schreiber. 2024. "Enhancing Antifungal Drug Discovery Through Co-Culture with Antarctic Streptomyces albidoflavus Strain CBMAI 1855" International Journal of Molecular Sciences, 25(23): 12744. https://doi.org/10.3390/ijms252312744 doi: https://doi.org/10.3390/ijms252312744
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16S_rRNA.zip
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MALDI_TOF.zip
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README.txt
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Published May 12, 2026
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MD5: 5947511113e6397bd08a904ace1bae54
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