Metadados de sinais de eletroencefalografia para caracterização da epilepsia pela Sincronização de Motifs: Coortes UNICAMP (EEG-fMRI) e TUH-SZ

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Costa, Leonardo Rodrigues da; Castellano, Gabriela, 2025, "Metadados de sinais de eletroencefalografia para caracterização da epilepsia pela Sincronização de Motifs: Coortes UNICAMP (EEG-fMRI) e TUH-SZ", https://doi.org/10.25824/redu/IBIQO5, Repositório de Dados de Pesquisa da Unicamp, V1
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Este repositório contém metadados referentes a três coortes distintas de eletroencefalograma (EEG), utilizados para a validação da metodologia de conectividade funcional por Sincronização de Motifs (MS) em contextos de epilepsia. O conjunto de dados primário consiste em registros de EEG de couro cabeludo adquiridos simultaneamente com ressonância magnética funcional (EEG-fMRI) na Universidade Estadual de Campinas (UNICAMP). Estes dados abrangem 75 pacientes com diferentes etiologias de epilepsia e três controles saudáveis, focando na atividade interictal. Deste grupo principal, destaca-se uma subcoorte curada de 10 pacientes com Epilepsia do Lobo Temporal Mesial (ELTM) e esclerose hipocampal confirmada. Adicionalmente, o repositório indexa metadados referentes a um subconjunto externo curado do Temple University Hospital Seizure Corpus (TUH-SZ), selecionado especificamente para avaliar a detecção de crises (atividade ictal) em montagens clínicas padrão. Detalhes dos bancos de dados: 1. Coorte EEG-fMRI (Geral) - Origem: UNICAMP (Campinas, SP, Brasil). - Participantes: 75 pacientes diagnosticados com epilepsia (33 do sexo masculino, idade média 39±12 anos) e 3 voluntários saudáveis (controles, 2 do sexo masculino). - Condição de Registro: Repouso (Resting-state) dentro do scanner de RM, durante estágio interictal. - Instrumentação: BrainCap MR (touca de EEG com eletrodos baseados em gel Ag/Cl, compatível com RM, BrainProducts). Canais: 64 eletrodos (Ag/AgCl), incluindo eletrodo de ECG. - Taxa de Amostragem: 5000 Hz (sinal bruto). - Referência de Aquisição: FCz (referência), AFz (terra). //// 2. Sub-coorte ELTM - Participantes: 10 indivíduos selecionados da coorte geral. - Critério de Inclusão: Diagnóstico de ELTM, presença de esclerose hipocampal em RM (T1/FLAIR) e descargas epileptiformes temporais focais no EEG. - Duração das Amostras: Segmentos selecionados variando entre 290 e 367 segundos, priorizando alta densidade de descargas interictais (IEDs). //// 3. Subconjunto TUH-SZ (Dados Externos) - Origem: Temple University Hospital Seizure Dataset (Open Access). - Amostragem: 500 aquisições provenientes de 261 pacientes únicos. - Instrumentação: EEG clínico de couro cabeludo padrão. - Configuração de Canais: 20 eletrodos (Sistema 10/20) + ECG. - Referência: Orelhas ligadas (Linked-ears). - Taxa de Amostragem: 250 Hz. - Conteúdo: Segmentos contendo crises epilépticas (ictais) e períodos interictais, pré-ictais e pós-ictais. Acesso externo ao dataset TUH-SZ: https://isip.piconepress.com/projects/tuh_eeg/ (2025-10-31)
Subject Medicine, Health and Life Sciences; Physics
Keyword Eletroencefalografia, EEG-fMRI, EEG, Conectividade funcional, Dinâmica não-linear, Epilepsia, Teoria de Grafos, Redes complexas, Neurociência
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