Síntese e caracterização in vitro de arcabouço de quitosana metacrilada/hidroxiapatita/β-TCP para regeneração do complexo dentino-pulpar

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Souza, Alana Pinto Carôso; Correr, Américo Bortolazzo, 2026, "Síntese e caracterização in vitro de arcabouço de quitosana metacrilada/hidroxiapatita/β-TCP para regeneração do complexo dentino-pulpar", https://doi.org/10.25824/redu/SPJLEJ, Repositório de Dados de Pesquisa da Unicamp, V1
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O conjunto de dados refere-se às informações obtidas a partir de experimentos laboratoriais realizados para avaliar arcabouços fotopolimerizáveis de quitosana metacrilada desenvolvidos para aplicações na regeneração do complexo dentina-polpa. Trata-se de um conjunto de dados primários, de natureza experimental e inteiramente in vitro, composto por variáveis obtidas a partir de ensaios de caracterização físico-química, morfológica, mecânica e biológica dos biomateriais desenvolvidos, incluindo dados de espectroscopia de ¹H-RMN, FTIR, análise termogravimétrica (TGA), microscopia eletrônica de varredura (MEV), quantificação de porosidade por análise de imagem, ensaios de compressão uniaxial, intumescimento em PBS, degradação ao longo do tempo e testes biológicos em cultura celular. O escopo do conjunto de dados abrange quatro grupos experimentais de arcabouços: quitosana (C), quitosana metacrilada (MAC), quitosana metacrilada associada à hidroxiapatita (MACHA) e quitosana metacrilada associada ao β-trifosfato de cálcio (MACBTCP), além de um controle comercial à base de agregado de trióxido mineral (MTA) utilizado nos ensaios celulares. Esses dados foram utilizados para avaliar propriedades estruturais, estabilidade físico-química, comportamento mecânico, perfil de degradação, citocompatibilidade e potencial de mineralização dos materiais, contribuindo para a compreensão do desempenho de biomateriais baseados em quitosana para aplicações regenerativas e permitindo a reprodutibilidade e reutilização dos dados em futuras pesquisas (2026-03-06)
Subject Medicine, Health and Life Sciences
Keyword Chitosan, Tissue engineering, Hydroxyapatite, Stem cell
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Published Mar 6, 2026
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