The role of the WNT5A protein in neoplasms

Version 1.0
The role of the WNT5A protein in neoplasms
Bueno, Maura Lima Pereira; Saad, Sara Teresinha Olalla, 2025, "The role of the WNT5A protein in neoplasms", https://doi.org/10.25824/redu/XYCRWT, Repositório de Dados de Pesquisa da Unicamp, V1
Learn about Data Citation Standards.
Contact Owner Share
Dataset Metrics
51 Downloads
Description
Characterizing the tumor microenvironment (TME) is vital for understanding the intricate cellular crosstalk within tumors and for identifying critical immunological markers. Given the TME's contribution to neoplasm development and progression, a comprehensive analysis can significantly advance cancer diagnosis, prognosis, and therapeutic interventions. Dysregulation of WNT signaling, notably WNT5A, is a key driver of tumorigenesis in multiple cancers. WNT5A, an evolutionarily conserved protein, displays context-dependent oncogenic or tumor-suppressive activities through modulation of non-canonical pathways, affecting cell growth, migration, and invasion. Therefore, understanding the role of this marker in different neoplasms, particularly hematological malignancies, is crucial for developing targeted therapies and improving patient outcomes. (2021-08-01)
Subject Medicine, Health and Life Sciences
Keyword WNT5A, Tumor microenvironment, Prognostic factor, Target therapy
Related Publication Bueno, M. L. P., Saad, S. T. O., & Roversi, F. M. (2022). WNT5A in tumor development and progression: A comprehensive review. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 155, 113599. https://doi.org/10.1016/j.biopha.2022.113599 doi: 10.1016/j.biopha.2022.113599
License/Data Use Agreement

CC BY-NC 4.0

Filter by
1 to 10 of 51 Files
3D.pzf
Unknown - 560.8 KB
Published Mar 24, 2025
1 Download
MD5: 20c00e2c7b99b82dac49875965b8c3ae
3D_coculture.png
3D_coculture.png
PNG Image - 575.4 KB
Published Mar 24, 2025
1 Download
MD5: 13d79e265f26fb8857e79260ffe91dc9
AO 2D HL60 72h.pzf
Unknown - 1.2 MB
Published Mar 24, 2025
1 Download
MD5: 75e5bc7ca27331b5f1a709b4d7f246a9
AO 2D K562 72h.pzf
Unknown - 1.3 MB
Published Mar 24, 2025
1 Download
MD5: 7f7855485f9da6dc2a58818d6dc695f5
AO 2D KG1 72h.pzf
Unknown - 1.3 MB
Published Mar 24, 2025
1 Download
MD5: b8ce513941436f687ee53217d402606b
AO 2D U937 72h.pzf
Unknown - 1.2 MB
Published Mar 24, 2025
1 Download
MD5: 80b31575be93d4f7b14075db0a7fdf92
AO HL60 72h.pzf
Unknown - 1.2 MB
Published Mar 24, 2025
1 Download
MD5: 4065ee371cf4162c7f55e3648128ee87
AO K562 72h.pzf
Unknown - 1.3 MB
Published Mar 24, 2025
1 Download
MD5: 6a56077534d8a637802453730710914a
AO KG1 72h.pzf
Unknown - 1.3 MB
Published Mar 24, 2025
1 Download
MD5: 4054a1d207a8e684fbab092d86bdc354
AO U937 72h.pzf
Unknown - 1.2 MB
Published Mar 24, 2025
1 Download
MD5: 4581c8c2f6268c7b7342a2cd1a605174
Edit File

This file has already been deleted (or replaced) in the current version. It may not be edited.

Restrict Access

Restricting limits access to published files. People who want to use the restricted files can request access by default. If you disable request access, you must add information about access to the Terms of Access field.

Learn about restricting files and dataset access in the User Guide.

Enable access request
You must enable request access or add terms of access to restrict file access.
Save Changes
Edit Embargo

The selected file or files have already been published. Contact an administrator to change the embargo date or reason of the file or files.
Delete Files

The file will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Select File(s)

Please select one or more files.

Share Dataset

Share this dataset on your favorite social media networks.

Dataset Citations

Citations for this dataset are retrieved from Crossref via DataCite using Make Data Count standards. For more information about dataset metrics, please refer to the User Guide.

Sorry, no citations were found.
Restricted Files Selected

The selected file(s) may not be downloaded because you have not been granted access.

Download Options

The files selected are too large to download as a ZIP.

You can select individual files that are below the 953.7 MB download limit from the files table, or use the Data Access API for programmatic access to the files.

Select File(s)

Please select a file or files to be downloaded.

Restricted Files Selected

The restricted file(s) selected may not be downloaded because you have not been granted access.

Click Continue to download the files you have access to download.

Delete Dataset

Are you sure you want to delete this dataset and all of its files? You cannot undelete this dataset.

Delete Draft Version

Are you sure you want to delete this draft version? Files will be reverted to the most recently published version. You cannot undelete this draft.

Unpublished Dataset Private URL

Private URL can only be used with unpublished versions of datasets.

Unpublished Dataset Private URL

Are you sure you want to disable the Private URL? If you have shared the Private URL with others they will no longer be able to use it to access your unpublished dataset.

Delete Files

The file(s) will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Compute

This dataset contains restricted files you may not compute on because you have not been granted access.

Deaccession Dataset

Are you sure you want to deaccession? The selected version(s) will no longer be viewable by the public.

Deaccession Dataset

Are you sure you want to deaccession this dataset? It will no longer be viewable by the public.

Version Differences Details

Please select two versions to view the differences.

Version Differences Details
 
Version:
Last Updated:
Version:
Last Updated:
Select File(s)

Please select a file or files for access request.

Select File(s)

Embargoed files cannot be accessed. Please select an unembargoed file or files for your access request.

Edit Tags

Select existing file tags or create new tags to describe your files. Each file can have more than one tag.

Request Access

  You need to Log In to request access.

Dataset Terms

This dataset is made available under the following terms. Please confirm and/or complete the information needed below in order to continue.

Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation shown on the dataset page.

CC BY-NC 4.0

Preview Guestbook

Upon downloading files the guestbook asks for the following information.

Account Information

Package File Download

Use the Download URL in a Wget command or a download manager to download this package file. Download via web browser is not recommended. User Guide - Downloading a Dataverse Package via URL

https://redu.unicamp.br/api/access/datafile/

Request Access

Please confirm and/or complete the information needed below in order to request access to files in this dataset.

Compute Batch
Clear Batch
Dataset Persistent Identifier Change Compute Batch
Compute Batch
Submit for Review

You will not be able to make changes to this dataset while it is in review.

Publish Dataset

Are you sure you want to republish this dataset?

Select if this is a minor or major version update.

Publish Dataset

This dataset cannot be published until Biomédicas is published by its administrator.

Publish Dataset

This dataset cannot be published until Biomédicas and Repositório de Dados de Pesquisa da Unicamp are published.

Return to Author

Return this dataset to contributor for modification.